Columbia
U.S.A. 1981
First Space Shuttle, launched in 1981, marking the beginning of the Space Shuttle program.
Discovery
U.S.A. 1984
Multiple missions, including the deployment of the Hubble Space Telescope and the return-to-flight mission after the Challenger disaster.
Buran
Russia 1998
Soviet space shuttle, flew only once (unmanned) in 1988 before the program was discontinued.